Background: Thrombolytic drugs to treat an acute ischaemic stroke reduce the risk of death or major disability. The treatment is, however, also associated with an increased risk of potentially fatal intracranial bleeding. This confronts the patient with the dilemma of whether or not to take a risk of a serious side effect in order to increase the likelihood of a favourable outcome. Objective: To explore acute stroke patients’ perception of risk and willingness to accept risks associated with thrombolytic drug treatment. (...) Design: Eleven patients who had been informed about thrombolytic drug treatment and had been through the process of deciding whether or not to participate in a thrombolytic drug trial went through repeated qualitative, semistructured interviews. Results: Many patients showed a limited perception of the risks connected with thrombolytic drug treatment. Some perceived the risk as not relevant to them and were reluctant to accept that treatment could cause harm. Others seemed to be aware that treatment would mean exposure to risk. The patients’ willingness to take a risk also varied substantially. Several statements revealed ambiguity and confusion about being involved in a decision about treatment. The patients’ reasoning about risk was put into the context of their health-related experiences and life histories. Several patients wanted the doctor to be responsible for the decisions. Conclusion: Acute stroke patients’ difficulties in perceiving and processing information about risk may reduce their ability to be involved in clinical decisions where risks are involved. (shrink)

Background: Informed consent is regarded as a contract between autonomous and equal parties and requires the elements of information disclosure, understanding, voluntariness and consent. The validity of informed consent for critically ill patients has been questioned. Little is known about how these patients experience the process of consent.Objective: The aim of this study was to explore critically ill patients’ experience with the principle of informed consent in a clinical trial and their ability to give valid informed consent.Design: 11 stroke patients (...) who had been informed about thrombolytic treatment and had been through the process of deciding whether or not to participate in a thrombolysis trial went through repeated qualitative semistructured interviews.Results: None of the patients had any clear understanding of the purpose of the trial. Neither did they understand the principles of randomisation and voluntariness. Reasons for giving or not giving consent were trust, conceptions of benefits and risks and altruism. Several patients found it immoral to involve patients in the consent procedure and argued that this was the doctors’ responsibility. Others argued that it is a duty to question patients and perceived it as a sign of being treated with respect and dignity. A majority of the patients found the consent process vague and ambiguous.Conclusions: The results indicate that the principle of informed consent from critically ill patients cannot be seen as a contract between equal and autonomous parties. Further studies are needed to explore critically ill patients’ experiences with the process of informed consent. (shrink)

Background: Informed consent is regarded as a contract between autonomous and equal parties and requires the elements of information disclosure, understanding, voluntariness and consent. The validity of informed consent for critically ill patients has been questioned. Little is known about how these patients experience the process of consent.Objective: The aim of this study was to explore critically ill patients’ experience with the principle of informed consent in a clinical trial and their ability to give valid informed consent.Design: 11 stroke patients (...) who had been informed about thrombolytic treatment and had been through the process of deciding whether or not to participate in a thrombolysis trial went through repeated qualitative semistructured interviews.Results: None of the patients had any clear understanding of the purpose of the trial. Neither did they understand the principles of randomisation and voluntariness. Reasons for giving or not giving consent were trust, conceptions of benefits and risks and altruism. Several patients found it immoral to involve patients in the consent procedure and argued that this was the doctors’ responsibility. Others argued that it is a duty to question patients and perceived it as a sign of being treated with respect and dignity. A majority of the patients found the consent process vague and ambiguous.Conclusions: The results indicate that the principle of informed consent from critically ill patients cannot be seen as a contract between equal and autonomous parties. Further studies are needed to explore critically ill patients’ experiences with the process of informed consent. (shrink)

Asheim, O. Om handlingsformidling.--Hellesnes, J. Hending, handling og aktør.--Apel, K.-O. Vår tids konflikter og muligheten for en etiskpolitisk grunnorientering.--Böhler, D. Å kunne handle, å kunne forstå, å kunne tale.--Nordenstam, T. Vetenskaplig kompetens.--Måseide, A. Perspektivitet, intensjonalitet, refleksjon.--Øfsti, A. Moral og erscheinungswelt hos Kant.--Haga, Å. Transcendentalfilosofi og refleksiv argumentasjon.--Skirbekk, G. Folkelege tankar om sikt og oversikt.--Johannessen, K. S. Mening, kontekst, praksis og transcendentalitet.--Kalleberg, R. Fra kritikk av positivismen til kritikk av kapitalismens politiske økonomi.--Slagstad, R. Struktur-funksjonalisme og historisk materialisme.--Wyller, E. A. Politisk (...) oppløsning og forfall ifølge Platon.--Høibraaten, H. Romantisk eller teknologisk refleksjon. (shrink)

Modern scholars have been concerned with the hostility shown to Alexander by the Hellenistic schools of philosophy. Two literary portraits have been distinguished, the Peripatetic and the Stoic, the former deriving from Theophrastus' book on Callisthenes, or starting with this work the Peripatetics worked out a theory of and applied it to Alexander, in order to belittle his achievements. It was a case of giving sophisticated expression to the kind of crude resentment expressed by Demades.

The locus classicus for Plutarch's own views on his methods is in the Alexander He has begun by asking for the indulgence of his readers if they do not find all the exploits of Alexander and Caesar recounted by the biographer or if they discover him not reporting some famous incident in detail (); and he goes on to compare his own search for evidence which will indicate the kind of soul, with the activity of the painter, who, in order (...) to create a likeness, concentrates on the eyes and pays little attention to the other parts. Commentators and critics have been right to take this as a key text for the purpose of understanding Plutarch's attitude towards his biographical work; nevertheless there are other passages in the Lives where we can at least glimpse his attitude to his subject, and we can only see the Alexander-remarks in correct perspective if we take these other passages into account. I propose therefore, starting with the Alexander, to see how far these critical remarks apply to Plutarch's theory and practice elsewhere in the Lives. (shrink)

According to the Ars Amatoria the notorious rape took place on the occasion of a primitive dramatic entertainment staged in a theatre, in which the seats and furnishings were also primitive. There is no time for a description of the arts of the performers—a tibicen and a ludius—before the Romans, impatient for action, receive their signal from Romulus. Nor is there any mention of a god in whose honour the entertainment had been provided.

Standard models of adolescent risk taking posit that the cognitive abilities of adolescents and adults are equivalent, and that increases in risk taking that occur during adolescence are the result of socio emotional differences in impulsivity, sensation seeking, and lack of self-control. Fuzzy-trace theory incorporates these socio emotional differences. However, it predicts that there are also cognitive differences between adolescents and adults, specifically that there are developmental increases in gist-based intuition that reflects understanding. Gist understanding, as opposed to verbatim-based analysis, (...) generally has been hypothesized to have a protective effect on risk taking in adolescence. Gist understanding is also an essential element of informed consent regarding risks in medical decision- making. Evidence thus supports the argument that adolescents’ status as mature minors should be treated as an exception rather than a presumption, because accuracy in verbatim analysis is not mature gist understanding. Use of the exception should be accompanied by medical experts’ input on the bottom-line gist of risks involved in treatment. (shrink)

The termination of rewrite systems for parameter recursion, simple nested recursion and unnested multiple recursion is shown by using monotone interpretations both on the ordinals below the first primitive recursively closed ordinal and on the natural numbers. We show that the resulting derivation lengths are primitive recursive. As a corollary we obtain transparent and illuminating proofs of the facts that the schemata of parameter recursion, simple nested recursion and unnested multiple recursion lead from primitive recursive functions to primitive recursive functions.

It is customary to consider late Imperial historiography as a barren waste of meagre and inaccurate chronicles and incompetent rhetorical epitomes, all overshadowed by the giant figure of Ammianus Marcellinus, the greatest literary genius, as E. Stein has called him , between Tacitus and Dante. In fact, however, the fifth century A.D. produced at least one writer who was, in the words of Niebuhr, ‘second to no historian even of the best ages in talent, good faith and wisdom; elegant and (...) very pure in style, he justly acquired praise and glory both among contemporaries and succeeding ages’. Niebuhr was referring to Priscus of Panium in Thrace, but Priscus was a member of a school of historical writing which had been founded earlier in the fifth century by Olympiodorus, an historian of scarcely less merit than Priscus and author of what J. B. Bury called ‘a highly important work’. Since even Schmid-Stahlin are not able to refer to a single essay or mono-graph on Olympiodorus, it may not be amiss to assemble the facts which are known about him and to try to discover, so far as the scanty materials permit, what sort of man he was and what sort of work he produced. (shrink)

The chief works of Tacitus and Apuleius have come down to us in a single Beneventan—i.e. South Italian—MS. of the eleventh century. The Annals and Histories of Tacitus, and the Apologia, Metamorphoses, and Florida of Apuleius, depend solely on the authority of the famous Florentine MS. preserved in the Laurentian Library under the press-mark 68.2. Any new light that can be thrown on such a MS. is of interest to classical scholars. With the portion of the MS. containing the works (...) of Tacitus the writer has dealt at some length in a paper read in April, 1913, in London before the International Congress of Historical Studies, which paper will be published shortly. Here it is proposed to deal with the portion containing the works of Apuleius, and with the oldest extant transcript of this portion, which is also in Beneventan writing, and is likewise preserved in the Laurentian Library under the press-mark 29.2. In the critical apparatus of Apuleius Laur. 68.2 is cited as F, and Laur. 29.2 as ø. (shrink)

A Few years ago Professor Souter made the suggestion that the curious custom of beginning each page of a MS., or each column of a page, with a large letter might be of African origin. He was struck with this feature while examining a fragment, newly acquired for the British Museum, of the celebrated Codex Palatinus of the Gospels , which is supposed to give us the African text of the New Testament. In reply to the suggestion, the present writer (...) submitted a list of eighteen MSS. in which this usage is illustrated. As most of the MSS. are manifestly Italian, the African origin of the practice was shown to be untenable. Quite recently another theory has been put forward, localizing the practice within still narrower limits. According to Professor Weinberger, the use of a capital at the beginning of each page would seem to be a peculiarity of MSS. coming from Cassiodore's library at Vivarium; and he proceeded to use this feature as a touchstone for detecting Codices Vivarienses. Impressed by the unusual interest attaching to this feature, I began to assemble all the instances I had, and to look for others. I collected a list of nearly fifty items, an inspection of which showed me at once that in registering the phenomenon under discussion I had unwittingly drawn up a list of very ancient MSS. The list does not, to be sure, hold all our oldest MSS., but most of those it holds are, as will be seen, among the oldest. In other words, the use of a large letter at the beginning of each page is clearly a custom of very great antiquity. This being so, it seemed useful to interrogate these MSS. further, in order to ascertain what other practices they have of interest to palaeographers. (shrink)

The Twenty-fifth Congress of the CPSU exercised a major influence on research on cardinal problems of world development, including the problems of war and peace, which were defined by the congress as the principal question of our time. The Peace Program propounded by the Twenty-fourth Party Congress was pursued and developed so extensively and integrally at the Twenty-fifth Congress that this historical document as a whole came to be termed the Peace Program of the Twenty-fourth and Twenty-fifth Congresses of the (...) CPSU. The Party undertook exceptionally extensive measures to implement the decisions of the Twenty-fifth Congress, and theoretical aspects of the problem of war and peace were comprehensively and profoundly argued and elaborated in the works of L. I. Brezhnev - and other leaders of the Party and Soviet government. (shrink)

As a contributory step toward a new edition of Du Cange's Glossarium mediae et infimae latinitatis, planned by the International Association of Academies, the British Academy has undertaken to publish a critical edition of mediaeval glossaries. The most important of these glossaries, because it constitutes the parent-compilation from which subsequent compilers of glossaries drew their material, is that pair known as Abstrusa and Abolita, found combined in the Vatican MS. 3321, which is the oldest extant MS. of purely Latin glossaries. (...) It is with the date and home of this MS. that the present note is concerned. (shrink)

In a reply to his Social Democratic opponents, who claimed that Marx's theory could only be realized in the developed capitalist countries, Lenin wrote in 1920:Russia achieved Marxism, the only correct revolutionary theory, by truly suffering through a half-century's history of unheard-of torments and sacrifices, unprecedented revolutionary heroism, incredible energy, and selfless seeking, learning, testing in practice, being disappointed, verifying, and making comparisons with the experience of Europe.

Since it is only natural that lovers of a great poet's work should seek to defend their favourite from the charge of plagiarism, most of the scholars who have discussed the problem of the relationship between the Medeas of Neophron and Euripides have, whether consciously or unconsciously, approached their task in no very impartial spirit. Yet the prejudice against acknowledging Euripides' indebtedness to his predecessor is an unreasonable one, for a great tragedy or a great work of art of any (...) kind must be aesthetically judged without regard to its forerunners. For instance, we do not think any the worse of Antony and Cleopatra or of its author when we notice that ‘The barge she sat in, like a burnish'd throne’, etc., and many other fine passages in that play are taken almost verbatim from Sir Thomas North. If we bear in mind then that whatever the result of our inquiry it will not affect adversely the reputation of Euripides' great work, we cannot fail to be impressed by the tenuous nature of the arguments by which scholars have convinced themselves of the chronological priority of Euripides' Medea as against Neophron's. (shrink)

Procopius, Bell. Goth. 8.20 , gives us information about Britain which is of the first importance, but I have not seen a convincing interpretation of what he says. Since the standard English translation, that of H. B. Dewing in the Loeb series , includes a number of unfortunate mistakes I rive a literal translation of some of Procnnius' sentences.

Although students of the fifth century A.D. have not been slow to recognize the merits of the ͉στορα Βυζαντιακ of Priscus, few efforts seem to have been made to under-stand this historian's methods of composition. The purpose of the present note is to indicate that the literary fashions of his time have exercised an unfortunate influence on at least one part of Priscus' work.